Prediabetes and Type 2 Diabetes in Aging

Launched by UŞAK UNIVERSITY · Apr 29, 2025

Keywords

ClinConnect Summary

Type 2 Diabetes Mellitus develops due to insulin resistance and/or decreased insulin secretion and is particularly common in the elderly population. With the aging process, metabolic changes and increased insulin resistance increase the risk of diabetes. Long-term complications of diabetes can negatively affect the quality of life in geriatric individuals with effects such as cognitive impairment, loss of physical function and fatigue. In individuals with diabetes, hyperglycemia, microvascular complications and inflammation can increase the risk of cognitive decline. This can pave the way f...

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Eligibility criteria

• Inclusion Criteria:
• • for people without diabetes (healthy), those with Hemoglobin A1c Levels (HbA1c) normal range between 4% and 5.6%,
• • those with HbA1c level between 5.7% and 6.4%, those with prediabetes (Impaired Glucose Tolerance),
• • those with 6.5% -7.5% level and
• • those with HbA1c level above 7.5
• • criteria are being 60 years of age and older,
• Exclusion Criteria:
• • those who have major depression,
• • uncontrolled thyroid disease,
• • those with vitamin B12, folic acid deficiency and anemia,
• • those with uncontrolled hypertension,
• • those with nephropathy and retrophy,
• • those with any neuropsychological disorder, a history of alcohol, substance or drug addiction,
• • those using any neurological or psychological medication (anticonvulsant drugs, antidepressants, anxiolytics, etc.),
• • those with Alzheimer's and Parkinson's disease,
• • those with cancer,
• • those with lung disease