Establishment of a Clinical and Prognostic Follow-up Cohort of Migraine Patients With Patent Foramen Ovale

Launched by PEKING UNIVERSITY THIRD HOSPITAL · Apr 29, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how migraines may be related to a heart condition called patent foramen ovale (PFO), which is a small hole in the heart that didn't close as it should after birth. The goal is to create a specialized headache center in China to better understand migraines, explore possible treatments for patients with both migraines and PFO, and identify factors that could affect how well patients respond to treatment.

To participate in this study, individuals need to have a diagnosis of migraines based on recognized guidelines and a confirmed diagnosis of PFO through specific heart imaging tests. The trial is open to people of all ages and genders who are willing to sign consent forms and participate in follow-up evaluations. If you join, you can expect to undergo various tests and assessments to help researchers learn more about these conditions and improve treatment options for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Meet the diagnostic criteria for migraine in the International Classification of Headache (ICHD-3);
• • Confirmation of patent foramen ovale through transthoracic echocardiography(TTE) or transesophageal echocardiography(TEE)/right heart contrast echocardiography
• • Agree to participate in the study and sign the informed consent form.
• Exclusion Criteria:
• • Can not sign the informed consent form or cooperate with follow-up.