Remotely Monitored, Mobile Health-supported, High Intensity Interval Training Before Hematopoietic Stem Cell Transplant

Launched by UNIVERSITY OF KANSAS MEDICAL CENTER · Apr 23, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a special exercise program called REMM-HIIT, which is monitored remotely, can improve fitness and physical abilities in patients who are about to undergo stem cell transplantation. The main questions researchers want to answer are whether this training helps participants get fitter and feel better physically. Participants in the study will be compared to a control group who won’t do the training to see if the exercise program makes a difference in their recovery after transplant.

To be eligible for this trial, participants need to be between 18 and 80 years old and planning to have a stem cell transplant in the next 4 to 12 weeks. They should be comfortable reading and writing in English and able to follow exercise coaching. Throughout the study, participants will complete various fitness tests, track their daily activity, and may even provide samples of blood and stool. This study is not yet recruiting, but it aims to help understand how exercise can support patients during a critical time in their treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Plan to undergo allogeneic hematopoietic stem cell transplant in 4-12 weeks after enrollment on this study.
• • Age 18-80 years
• • Able to read/write English (as many participant-reported outcome measures lack validated translations in other languages)
• Exclusion Criteria:
• • Unable or unwilling to follow coaching
• • Functional impairment resulting in inability to exercise
• * Any absolute contraindications to exercise:
• • 1. recent (\<6 months) acute cardiac event;
• • 2. unstable angina;
• • 3. uncontrolled dysrhythmias causing symptoms;
• • 4. symptomatic aortic stenosis;
• • 5. uncontrolled symptomatic heart failure;
• • 6. acute pulmonary embolus;
• • 7. acute myocarditis or pericarditis;
• • 8. suspected or known dissecting aneurysm