16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy

Launched by UNIVERSITY HOSPITAL, BASEL, SWITZERLAND · Apr 25, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at the difference in pain levels after surgery between two types of chest drains used for patients who have undergone a specific lung surgery called thoracoscopic lobectomy or segmentectomy. The researchers want to find out if using a smaller chest drain (16F) leads to less pain compared to the standard larger drain (24F). This study is important because managing pain effectively can help patients recover more comfortably after their surgery.

To participate in this trial, individuals need to be between 18 and 80 years old and have a specific type of lung cancer that can be surgically treated. Participants will need to sign a consent form and must meet certain health criteria, such as not having had previous thoracic surgery in the last six months. If eligible, patients can expect to have their pain levels monitored after surgery to see how the size of the chest drain affects their recovery experience. It's also important to note that this trial is not yet recruiting participants, so those interested will have to wait for it to start.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Informed Consent signed by the patient (all sex and gender)
• • Patients' age from ≥ 18 to ≤ 80 at time of study inclusion
• • American Society of Anaesthesiologists (ASA) physical status classification I to III
• • Patients with resectable non-small cell lung cancer (NSCLC) deemed operable by minimally invasive surgical technique (UICC Stages 0-II according to Tumor Nodes Metastasis (TNM) Classification 8th edition and selected patients with UICC Stage IIIA) or pulmonary metastasis or pulmonary lesion resected by lobectomy and/or segmentectomy
• • Minimally invasive anatomical lung resections under general anaesthesia: lobectomy, lobectomy with wedge resection, lobectomy combined with segmentectomy, segmentectomy with wedge resection, bilobectomy
• Exclusion Criteria:
• • Previous thoracic surgery on the same side within 6 months
• • Lung cancer complicated with pleural empyema
• • Patients with chronic pain who receive opiates/gabapentin/pregabalin
• • Patients who consume opiates/benzodiazepines
• • Congestive heart failure NYHA Class III or IV
• • Liver cirrhosis Child-Pugh Class B and C
• • Renal insufficiency requiring dialysis and/or estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73 m2
• • Patients with coagulopathy or bleeding disorders: von Willebrand disease, Hemophilia; Thrombocytopenia (\<50 G/l), requiring platelet transfusion
• • Patients with neuralgia
• • Chest pain (site of surgery) without taking painkillers, measured by VAS while coughing \> 10 mm
• • Rib fractures (in the last 3 months) on the side of surgical procedure
• • Open anatomical lung resection, including pneumonectomy
• • Insertion of 2 or more chest tubes
• • Need for patient controlled intravenous anaesthesia or patient controlled epidural anaesthesia
• • Patients intubated/sedated (not suitable due to difficulties to fill out the pain survey)