Resistance Exercise Training on Vascular and Physical Function in Postmenopausal Women

Launched by NATIONAL YANG MING CHIAO TUNG UNIVERSITY · Apr 28, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how a specific type of exercise, called whole-body progressive resistance training, can help improve blood vessel health and muscle strength in postmenopausal women. After menopause, many women may experience health issues like weaker muscles and blood vessels, which can increase the risk of heart disease. The researchers want to see if this exercise program can make a positive difference in both muscle strength and blood flow, ultimately helping women maintain their independence and overall health.

To participate in the study, women need to be between 55 and 70 years old, have a body mass index (BMI) under 30, and have been postmenopausal for at least a year. They should also be able to live independently and communicate in Mandarin or Taiwanese. However, there are some reasons why a woman might not be eligible, such as recent injuries, certain serious health conditions, or if she is currently taking specific medications. Participants can expect to engage in a structured exercise program designed to enhance their physical well-being over time.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• Participants were eligible for the study if they met the following criteria:
• • 1. Postmenopausal women aged between 55 and 70 years;
• • 2. Body mass index (BMI) less than 30 kg/m²;
• • 3. At least one year since menopause;
• • 4. Able to live independently in the community;
• • 5. Able to communicate independently in Mandarin or Taiwanese.
• Exclusion Criteria:
• Participants were excluded if they met any of the following conditions:
• • 1. Acute musculoskeletal injuries within the past month (e.g., acute inflammation, fractures, sprains, contusions, or joint implants);
• • 2. Diagnosed central or peripheral nervous system disorders affecting exercise participation (e.g., stroke, dementia, Parkinson's disease, autonomic dysfunction);
• • 3. History of serious cardiac conditions within the past six months (e.g., coronary stenting, pacemaker implantation, peripheral or cerebral vascular reconstruction);
• • 4. Presence of peripheral vascular diseases (e.g., peripheral artery disease, venous thrombosis);
• • 5. Hormone therapy within the past six months;
• • 6. Currently taking beta-blockers, anti-inflammatory drugs, or anticoagulant medications;
• • 7. Currently participating in any other structured exercise training programs.