Oxygen Therapy in Diabetic Kidney Disease

Launched by ASSIUT UNIVERSITY · Apr 28, 2025

Keywords

ClinConnect Summary

This clinical trial, titled "Oxygen Therapy in Diabetic Kidney Disease," is looking at how oxygen therapy might help people with diabetic kidney disease (DKD). DKD is a serious condition that can lead to end-stage kidney disease, where the kidneys can no longer function properly. This trial aims to explore if providing extra oxygen could improve kidney health in patients who have diabetes and certain levels of kidney damage.

To be eligible for this trial, participants must be adults over 18 years old who have diabetic kidney disease, specifically those with a certain level of kidney function and protein in their urine. Unfortunately, individuals under 18, those with heart disease, chronic lung conditions, or other serious kidney issues, as well as pregnant or nursing women, cannot participate. If someone is eligible and decides to join, they can expect to receive close monitoring and support throughout the study to see how oxygen therapy affects their kidney health. This trial is not yet recruiting participants, so it is still in the planning stages.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Diabetic male and female patients aged \> 18 yrs with diabetic kidney disease (eGFR 30-90 mL/min/1.73m² and proteinuria \>300 mg/day)
• Exclusion Criteria:
• • Age \< 18 yrs
• • Cardiovascular disease (thorough assessment of the patient's medical history (symptoms suggestive of CVD (e.g., chest pain, shortness of breath, fatigue), family history of CVD and risk factors (e.g., hypertension, hyperlipidemia, smoking). Physical Examination including blood pressure measurement, auscultation of heart sounds and assessment of peripheral pulses. Additional Diagnostic Tests: Stress test (stress ECG and stress echocardiography): Evaluate cardiac function under stress, which can help detect coronary artery disease or other CVD.
• • Chronic lung disease (COPD, pulmonary fibrosis ...
• • Other chronic disease affecting kidney function (lupus nephritis).
• • Pregnancy or lactation.