ThyMoves: Screening and Exercise to Improve Muscle, Enhance Quality of Life, and Reduce Fall Risk in Thyroid Disease

Launched by AALBORG UNIVERSITY HOSPITAL · May 5, 2025

Keywords

ClinConnect Summary

The ThyMoves clinical trial is designed to help improve the quality of life for adults with thyroid disorders, specifically focusing on conditions like Hashimoto's thyroiditis and multinodular toxic goiter. The main goal is to see how a tailored exercise program can impact overall health and wellbeing. Participants will answer questions about their health-related quality of life, and those who meet certain criteria will join a program that includes both screening and exercise interventions. The trial will involve women who are at least 65 years old and have been stable in their thyroid hormone levels for at least six months.

If you’re eligible, you can expect to take part in surveys about your health and engage in a personalized exercise routine aimed at improving strength, balance, and overall health. The study aims to recruit a total of 148 participants, with specific criteria for inclusion, such as being free from certain serious health conditions and not currently involved in other exercise programs. This research hopes to identify ways to enhance the wellbeing of individuals living with thyroid disorders, ultimately helping to reduce their risk of falls and improve their everyday life.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Women with minimum 65 years of age, with no upper limit.
• • 2. Verified diagnosis of HT or MNTG
• • 3. Euthyroid for at least 6 months
• • 4. Signed the informed consent
• Exclusion Criteria:
• • 1. Current participation in a structured exercise program or regular physical exercise activity above 5 hours per week
• • 2. Previous experience with rhythm-based multitask exercise.
• • 3. Diagnosed with significant neurological diseases (e.g. Multiple Sclerosis and myasthenia gravis), vestibular diseases or newly orthopedic surgeries (e.g. knee or hip replacement)
• • 4. Fully dependent on walking aids
• • 5. Active malignancy or terminal illness
• • 6. Inability to understand Danish written and/or verbally
• • 7. Having severely impaired cognitive function, defined as a score below 8 on the cognitive assessment "the short orientation-memory-concentration test"
• • 8. Treatment with amiodarone within the last year
• • 9. No changes within the last six months in medications affecting weight or body composition - e.g., GLP-1 electrolyte/fluid balance - e.g., diuretics or corticosteroid
• • 10. Participation in other clinical intervention studies within the last six months
• For the cross sectional survey:
• Inclusion criteria:
• • 1. Men and women with a minimum of 18 years
• • 2. Diagnosis of primary hypothyroidism or primary hyperthyroidism