Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort

Launched by FIRST AFFILIATED HOSPITAL OF WANNAN MEDICAL COLLEGE · May 6, 2025

Keywords

ClinConnect Summary

The Cerebral Large Vessel Occlusion Stroke Multiomics Biosample Cohort trial is studying how to better understand and treat a type of stroke called acute ischemic stroke with large vessel occlusion (AIS-LVO). This study involves collecting various samples, such as blood and thrombi (clots), from patients at five different stroke centers. Researchers aim to create a comprehensive biobank that includes not just biological samples but also detailed clinical information and follow-up data. This research will help improve our understanding of strokes and potentially lead to better treatments in the future.

To participate in this trial, individuals must be over 18 years old and have a confirmed diagnosis of a large vessel occlusion ischemic stroke. They also need to provide blood or clot samples and give their consent to join the study. Participants can expect to share their medical information and undergo follow-ups, helping researchers gather valuable data. It’s important to know that if someone does not want to participate or cannot provide samples, they will not be eligible for the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age over 18 years.
• • 2. Patients with intracranial and extracranial large vessel occlusion ischemic stroke confirmed by cerebrovascular angiography.
• • 3. Availability of complete clinical and follow-up information required for the study.
• • 4. Availability of blood and/or thrombus biological samples.
• • 5. Voluntary written informed consent signed by the patient or their family (1) For retrospectively enrolled patients, a "broad informed consent" was signed at the time of sample collection. Upon enrollment into the cohort, a follow-up phone call was made to confirm the informed consent.
• • (2) For prospectively enrolled patients, informed consent for this study was signed at the time of enrollment by the patient or their family.
• Exclusion Criteria:
• • 1. Patients for whom biological samples cannot be obtained;
• • 2. Patients or their family members who refuse to sign the informed consent form.