The Use of Artificial Intelligence Generated Contours in Radiation Planning of the Prostate Brachytherapy

Launched by MARTIN KING, MD, PHD · May 1, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring how artificial intelligence (AI) can assist doctors in creating personalized radiation treatment plans for men with prostate cancer. Specifically, the study looks at how AI can help outline the prostate on ultrasound images during a type of radiation therapy known as brachytherapy. This specialized treatment involves placing small radioactive seeds directly into the prostate to kill cancer cells.

To be eligible for this trial, participants must be 18 years or older and considered suitable candidates for a whole gland high-dose rate (HDR) brachytherapy procedure. However, those who have had certain previous treatments, like permanent seed implants or specific surgeries on the prostate, may not qualify. While the study is not yet recruiting participants, those who join can expect to contribute to important research that could improve radiation planning for prostate cancer in the future.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age and older
• • Deemed suitable candidates for whole gland HDR prostate brachytherapy under general anesthesia as a monotherapy, boost or salvage treatment.
• Exclusion Criteria:
• • Prior permanent seed LDR brachytherapy implant
• • Prior transurethral resection of the prostate (TURP)
• • Presence or insertion of a rectal spacer
• • Focal HDR brachytherapy treatment i.e. not whole prostate