Use of Different Enteral Feeds to Impact on Chyle Leaks in Oesophagectomy
Launched by ROYAL COLLEGE OF SURGEONS, IRELAND · May 1, 2025
Trial Information
Current as of July 24, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the use of a special type of nutrition feed, called medium chain triglyceride (MCT) feeds, to see if it can help reduce the risk of chyle leaks after surgery for oesophageal cancer. Oesophagectomy is a surgery to remove part of the oesophagus, which can sometimes lead to complications like chyle leaks. Chyle is a fluid that helps transport nutrients in the body, and a chyle leak means that this fluid escapes where it shouldn’t. This can require extra medical care, like keeping a drainage tube in place or even additional procedures. The researchers want to find out if using MCT feeds right after surgery could lower the chances of this happening.
Adults over 18 years old who are scheduled for minimally invasive oesophagectomy for oesophageal cancer at Beaumont Hospital may be eligible to participate in this trial. To join, patients must be able to give informed consent and receive a specific type of feeding tube during or before their surgery. Participants in the trial can expect to receive either the standard type of feed or the new MCT feed and will help researchers understand if the MCT feed can make a difference in recovery. This study is currently not recruiting participants but aims to improve care for future patients undergoing this important surgery.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All adults aged over 18 years undergoing MIO or RAMIO for oesophageal cancer (adenocarcinoma and squamous cell cancer) at Beaumont Hospital will be approached for inclusion.
- Exclusion Criteria:
- • Patients will be excluded if
- • They are unable to provide informed consent
- • They do not receive a feeding jejunostomy at or prior to their oesophagectomy
- • Prior or concomitant malignancy that would interfere with this protocol
About Royal College Of Surgeons, Ireland
The Royal College of Surgeons in Ireland (RCSI) is a prestigious educational and research institution dedicated to advancing surgical practice and healthcare through innovative research, education, and clinical excellence. As a clinical trial sponsor, RCSI plays a pivotal role in conducting cutting-edge research that aims to improve surgical outcomes and patient care. With a commitment to fostering collaboration among healthcare professionals, researchers, and industry partners, RCSI is at the forefront of developing evidence-based interventions and therapies that address critical health challenges. Through its rigorous scientific approach and adherence to ethical standards, RCSI strives to contribute significantly to the advancement of medical knowledge and the enhancement of surgical practices globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported