Assessment of Eye Movements in Stroke Patients and Closed-loop Intervention

Launched by IRCCS SAN CAMILLO, VENEZIA, ITALY · May 1, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how eye movements can help understand problems with visual perception in people who have had a stroke. Researchers believe that tracking how the eyes move while looking at different things might reveal issues with how the brain processes visual information after a stroke. The study will also test a new training program that uses sounds to help improve these visual skills.

To participate in this trial, individuals need to be between the ages of 65 and 74 and must have had a first stroke that is either caused by a blockage (ischemic) or bleeding (hemorrhagic). They should be alert and show some visual or memory challenges, confirmed by brain scans. However, those who have had previous strokes, have multiple brain issues, or cannot stay alert during tests won’t be eligible. Participants will undergo assessments involving eye movements and may engage in visual training exercises to see if they can improve their visual skills.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Vigilant
• • First unifocal ischemic or hemorragic stroke
• • Presence of maximum two lacunae, clinically silent, smaller than 15 mm. in the structural MRI
• • Evident symptoms in the visual, attentive, memory, motor or language domain supported by the radiological exam
• Exclusion Criteria:
• • Previous stroke history, visible at the radiological exam
• • Multifocal deficit
• • Incapacity to remain vigilant during the required assessments
• • Claustrophobia and/or metallic objects which could prevent MRI acquisition
• • Presence of other neurological, psychiatric or medical conditions which may undermine interpretation of behavioral and neuroimaging results