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Search / Trial NCT06966817

The Effect of Two Different Oral Care Solutions on Ventilator-Associated Pneumonia and Oral Health of Mechanically Ventilated Patients in the Intensive Care Unit

Launched by SAGLIK BILIMLERI UNIVERSITESI · May 4, 2025

Trial Information

Current as of July 27, 2025

Enrolling by invitation

Keywords

Ventilator Associated Pneumonia , Oral Health Ventilator Associated Pneumonia ,Oral Health

ClinConnect Summary

Ventilator-associated pneumonia (VAP) is defined as pulmonary parenchymal infection in patients exposed to invasive mechanical ventilation for at least 48 hours and is a part of intensive care unit (ICU)-acquired pneumonia. Ventilator-associated pneumonia is the most common intensive care unit (ICU)-acquired infection among patients receiving invasive mechanical ventilation. When the VAP data of surgical and medical ICUs of thirty-six developing countries, including our country, for the years 2013-2018 were evaluated; the average VAP rate was determined as 11.47 per 1000 ventilator days. It...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:• Being 18 years of age or older
  • Requiring mechanical ventilation for at least 48 hours
  • Not having a diagnosis of aspiration pneumonia
  • Having a Clinical Lung Infection Score (CPIS) \<6 on the first day
  • Not having a diagnosis of pneumonia or COVID
  • Not having facial or oral trauma
  • Being within the first 24 hours of the intubation process
  • Not having a medical impediment to elevating the head of the bed 30o
  • Exclusion Criteria:
  • Not accepting to participate in the study
  • Termination of MV support for less than 48 hours
  • Being allergic to any of the solutions to be used in oral care
  • Being diagnosed with immunodeficiency
  • Having thrombocytopenia, leukopenia and oral aphthae, stomatitis, candidiasis, gingivitis
  • Using immunosuppressive drugs

About Saglik Bilimleri Universitesi

Saglik Bilimleri Universitesi, or the University of Health Sciences, is a leading academic institution dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on interdisciplinary collaboration, the university focuses on translating scientific discoveries into practical applications that enhance patient care and public health outcomes. Its commitment to rigorous ethical standards and comprehensive training equips researchers and healthcare professionals to contribute effectively to the global medical community. Through its clinical trial initiatives, Saglik Bilimleri Universitesi aims to address pressing health challenges and foster the development of new therapeutic strategies.

Locations

Ankara, , Turkey

Patients applied

0 patients applied

Trial Officials

bediye öztaş

Principal Investigator

Saglik Bilimleri Universitesi

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported