Effect of Trendelenburg Positioning on Anesthesia-Induced Hypotension in Elderly Patients

Launched by ZHEJIANG CANCER HOSPITAL · May 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how a specific position called the Trendelenburg position can help prevent low blood pressure, or hypotension, in elderly patients during surgery. The trial will involve patients aged 65 to 90 years who are scheduled for abdominal surgery with general anesthesia. Some patients will be placed in the Trendelenburg position, where their legs are elevated, while others will remain lying flat (the supine position) when the anesthesia starts. Researchers will closely monitor blood pressure during the first 15 minutes after anesthesia to see which position better keeps blood pressure stable.

To be eligible for this trial, patients must be between 65 and 90 years old, have a scheduled abdominal surgery, and be in generally good health (classified as ASA physical status I to III). However, some people may not qualify if they have certain health issues, such as difficulties with breathing or swallowing, or if they cannot provide consent for participation. It's important for potential participants and their families to understand that this trial is designed to improve care for older adults during surgery by finding better ways to manage blood pressure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • patients aged 65-90 years
• • scheduled for abdominal surgery with general anesthesia
• • expected to have continuous radial arterial pressure monitoring
• • American Society of Anesthesiologists (ASA) physical status I to III
• Exclusion Criteria:
• • contraindications or failure of radial arterial catheterization
• • expected possible difficult airway
• • non-sinus rhythm
• • increased intracranial pressure
• • patients at high risk of regurgitation or aspiration
• • inability to provide consent