Herbal Irrigation in Necrotic Primary Molars
Launched by CAIRO UNIVERSITY · May 9, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the use of a natural herbal solution called Frankincense to treat necrotic primary molars, which are baby teeth that have become infected and painful. The goal is to see how effective Frankincense is compared to the commonly used treatment, sodium hypochlorite, during a procedure called pulpectomy, which is similar to a root canal. Currently, there haven't been any studies comparing these two treatments specifically for baby teeth, so this research could provide valuable information.
To participate in this trial, children aged between 4 and 9 years old with specific dental issues may be eligible. Key criteria include having a primary molar with deep decay, pain, and signs of infection, but the tooth must still be restorable. Children who are uncooperative, have certain health conditions, or whose parents do not give permission to participate will not be included. If a child joins the study, they can expect to receive either the herbal treatment or the standard treatment during their dental visit, and the results will help improve future care for similar dental issues in children.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Mandibular primary molars with deep caries and necrotic pulp.
- • Mobility independent from normal physiological exfoliation
- • Pain on percussion.
- • Presence of fistula or furcation abscess.
- • Restorable tooth
- • Radiolucency in periapical or furcation area.
- • Widening of PDL space or loss of lamina dura continuity.
- • At least 2/3 root is present
- Exclusion Criteria:
- • Uncooperative children to avoid time waste and attrition bias.
- • Children with systemic disease as some systemic diseases may affect the outcome.
- • Lack of informed consent by the child patient's parent to be approved ethically.
- • Refusal of participation.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, El Manial, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported