Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars

Launched by CAIRO UNIVERSITY · May 10, 2025

Keywords

ClinConnect Summary

This clinical trial is looking to compare two different solutions used during dental treatments for children with unhealthy primary (baby) molars that need to be cleaned out—specifically, Moringa Oleifera leaf extract and sodium hypochlorite. These solutions are used to help kill harmful bacteria in the tooth. The study will measure how well each solution works by checking the reduction of bacteria in the tooth after treatment.

To participate in this trial, children must be between 4 to 7 years old and have been diagnosed with specific dental issues that require treatment. They should be healthy and able to cooperate during the dental procedure. However, children with certain dental conditions or those who are unwell may not be able to join. If eligible, participants can expect to receive routine dental care while contributing to important research that could help improve treatments for kids in the future. This trial is not yet recruiting participants, so there will be more information available once it begins.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged 4 to 7 years
• • Clinically and radiographically diagnosed with nonvital primary molars requiring pulpectomy
• • Cooperative children who can undergo dental treatment
• • Healthy-appearing children with no systemic, physical, or mental disorders
• Exclusion Criteria:
• • Medically compromised or uncooperative children
• * Primary molars indicated for extraction due to:
• • Advanced root resorption (more than two-thirds)
• • Teeth near exfoliation
• • Deep subgingival caries preventing proper restoration
• • Excessive mobility (Miller's Grade 2 or higher)