Vacuum-assisted Laser Ablation (VALA) for Treatment of Large Saphenous Veins

Launched by CENTER OF PHLEBOLOGY · May 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called Vacuum-assisted Laser Ablation (VALA) for patients with large varicose veins, also known as incompetent saphenous veins. The goal is to see if using a vacuum to remove blood during the procedure can make the treatment safer and more effective. Varicose veins can cause discomfort and other symptoms, and traditional treatments sometimes have risks, like blood clots or incomplete results. By using this new method, the researchers hope to reduce these risks and help patients recover more quickly.

To participate in the trial, you need to be over 18 years old and have varicose veins that are at least 15 mm in diameter. You should also be able to give informed consent and be willing to wear compression stockings after the procedure. However, certain conditions might exclude you, such as being pregnant, having certain health issues, or a history of serious blood clots. If you join the trial, you can expect to receive treatment and be monitored for safety and effectiveness, contributing to important research that could improve varicose vein treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age over 18 years
• • Varicose veins of the lower extremities with clinical class C2-C6 with a diameter of the GSV or SSV ≥ 15 mm in a standing position
• • Informed consent
• Exclusion Criteria:
• • pregnancy or lactation
• • malignant neoplasms
• • inability or unwillingness of any patient to wear compression stockings
• • hypersensitivity to lidocaine
• • concomitant diseases: diabetes mellitus, bronchial asthma, severe liver and kidney diseases, acute thrombosis and thrombophlebitis, skin and/or soft tissue infection, infectious diseases, obliterating peripheral arteriosclerosis, diabetic angiopathy, heart defects requiring surgical intervention, fever, toxic hyperthyroidism, obesity, tuberculosis, sepsis, blood cell composition disorder, all diseases requiring bed rest, heart disease with decompensation, known hereditary thrombophilia
• • period after treatment for alcohol addiction
• • sedentary lifestyle
• • history of acute deep vein thrombosis
• • history of superficial thrombophlebitis
• • history of drug or other addiction
• • use of oral contraceptives or other hormonal drugs