Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation

Launched by HOSPITAL FOR SPECIAL SURGERY, NEW YORK · May 6, 2025

Keywords

ClinConnect Summary

This clinical trial is focused on understanding cervical radiculopathy, a condition where nerve roots in the neck become pinched, causing pain and weakness. Researchers are looking at different ways to diagnose and predict how well patients will respond to treatments. They will use a special type of imaging called magnetic resonance neurography (MRN) alongside other tests to see how these methods work together. The goal is to find out if these tests can help improve treatment outcomes for patients.

To participate in this study, you should be between 18 and 60 years old and have symptoms of one-sided cervical radiculopathy that started between 2 to 12 weeks before your first visit. You will need to have an MRI that shows signs of nerve compression. However, if you’ve had previous neck surgery or other specific conditions like a stroke, you may not qualify. If you join the trial, you can expect to undergo imaging and other tests, and your responses to treatments will be monitored to see how effective they are. This research could lead to better ways to diagnose and treat neck pain in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients presenting with symptoms compatible with acute or subacute unilateral (one-sided) cervical radiculopathy and signs of clinical weakness
• • 18-60 years old at the time of evaluation
• • Symptom onset of 2 to 12 weeks leading up to baseline visit
• • Diagnosis of unilateral cervical radiculopathy, with or without spinal cord compression, based on signs and symptoms, physical exam and supported by MRI findings of radiculopathy (as evidenced by foraminal stenosis/narrowing) based on standard-of-care cervical spine MRI
• • Patients who have undergone or have planned electrodiagnostic testing at HSS prior to surgery
• Exclusion Criteria:
• • Prior cervical surgery or instrumentation
• • Those who have had a prior episode of cervical radiculopathy
• • History of peripheral neuropathy or another acute or chronic neurodegenerative condition
• • History of stroke, cerebellar disease, or central nervous system disease
• • Contraindications to undergoing a standard MRI examination (e.g., pregnancy)
• • Patients presenting with bilateral cervical radiculopathy