Assessing the Impact of a Leucine Enriched Whey Protein vs Isonitrogenous Whey on Muscle Protein Synthetic Responses in the Rested and Acute Post Exercise States in Older Adults

Launched by UNIVERSITY OF NOTTINGHAM · May 6, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how a special type of whey protein, enriched with leucine (an important amino acid), affects muscle health in older men. As we age, we can lose muscle mass and strength, which can lead to more health issues. This study aims to see if this "super-whey" protein helps older adults build muscle better than regular whey protein, both when they are at rest and after exercise.

To participate in the trial, you need to be a healthy man over 65 years old and meet certain health criteria, such as having a body mass index (BMI) between 18 and 35 and no serious heart or lung diseases. If you join the study, you can expect to consume different types of protein supplements while your muscle responses are carefully monitored. This research is important as it may help find better nutritional strategies to maintain muscle health in older adults.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• Exclusion Criteria:
• • A BMI \<18 or \>35 kg/m2
• • Active cardiovascular, cerebrovascular or respiratory disease: e.g. uncontrolled hypertension (BP \> 160/100), angina, heart failure (class III/IV), arrhythmia, right to left cardiac shunt, recent cardiac event, COPD, pulmonary hypertension or recent (6 mo) stroke
• • Any metabolic disease
• • Clotting dysfunction
• • A history of, or current neurological or musculoskeletal conditions (e.g. epilepsy)
• • Lactose intolerance
• • Having taken part in a research study in the last 3 months involving invasive procedures or an inconvenience allowance