Effects of Pulmonary Rehabilitation on Quality of Life and Health in Pulmonary Arterial Hypertension Patients

Launched by BEIJING CHAO YANG HOSPITAL · May 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how pulmonary rehabilitation can improve the quality of life and health for patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). Pulmonary hypertension is a serious lung condition that makes it hard to breathe and can lead to worsening health over time. The trial aims to see if a structured rehabilitation program can help patients feel better and improve their ability to exercise, which can be crucial for managing their symptoms.

To participate in this trial, individuals must be at least 18 years old and have a confirmed diagnosis of pulmonary hypertension. They should also have been on specific medications or treatments for a certain period, depending on whether they have PAH or CTEPH. Participants will need to provide written consent to take part in the study. Throughout the trial, participants can expect to engage in exercises designed to improve their lung function and overall well-being. This research is important because it seeks to fill a gap in understanding how rehabilitation can benefit these patients, alongside their usual medical treatments.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:Confirmed PH Diagnosis:
• • Right heart catheterization-confirmed pulmonary hypertension
• Meets 2022 ESC/ERS Guidelines diagnostic criteria for:
• • Group 1 (PAH) or
• • Group 4 (CTEPH/other pulmonary artery obstructions)
• Stabilized Treatment Status:
• • Group 1 (PAH): Received ≥3 months of targeted drug therapy
• • Group 4 (CTEPH): Completed ≥6 sessions of BPA\* or reached therapeutic endpoint
• Functional Capacity:
• • WHO Functional Class I-III
• • Age: ≥18 years
• • Consent: Willing to provide written informed consent -
• Exclusion Criteria:Physical Limitations:
• • Unable to perform pulmonary rehabilitation exercises due to disability or congenital malformations
• Cardiopulmonary Testing Contraindications:
• • Medically unfit to complete CPET (cardiopulmonary exercise testing) after evaluation
• Poor Compliance:
• • History of non-adherence making protocol completion unlikely
• Life Expectancy:
• • Prognosis ≤1 year
• • -