Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement

Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · May 7, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how different types of numbing medicine can affect pain levels during the placement of an IUD (a small device used for birth control). Specifically, the researchers want to see if a "buffered" version of lidocaine, which includes a small amount of sodium bicarbonate, is more effective at reducing pain compared to the regular (or "unbuffered") lidocaine. The study will also look at how patients feel about the empathy shown by their healthcare providers during the procedure.

To participate in this trial, women aged 18 to 50 who have never given birth (known as nulliparous women) and are seeking an IUD can apply. Participants should be able to speak English and provide informed consent. Importantly, they should not have a history of certain medical conditions, including chronic pain, substance use disorders, or any current pregnancy. If eligible, participants can expect to receive either the buffered or unbuffered lidocaine before their IUD placement, and their pain levels and experiences will be evaluated throughout the process. This research aims to improve the comfort and care women receive during this important procedure.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Ability to provide informed consent
• • 2. Women IUD placement for contraception or heavy menstrual bleeding
• • 3. Ages 18-50
• • 4. English-speaking
• • 5. Participants must not have a past medical history of substance use disorders, pain disorders, use of prescription pain medications or are found to be pregnant
• • 6. Nulliparous (never given birth)
• Exclusion Criteria:
• • 1. History of ever giving birth
• • 2. Current use of prescription pain medication prior to procedure. Over-the-counter medications such as those containing ibuprofen, aspirin, acetaminophen, or naproxen are allowed.
• • 3. Diagnosed chronic pain condition
• • 4. Current pregnancy
• • 5. Known allergic reactions to components of the local anesthetic
• • 6. History of an IUD placement
• • 7. Current substance use or history of substance use
• • 8. Known contraindications to IUD, such as unexplained vaginal bleeding