Effects of Blood Flow Restriction Training on Muscle Strength and Physical Function for Stroke-Related Sarcopenia

Launched by THE HONG KONG POLYTECHNIC UNIVERSITY · May 7, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a special exercise method called Blood Flow Restriction (BFR) walking on muscle strength and physical function in patients who have had a stroke and are experiencing muscle loss, known as sarcopenia. The main goal is to see if BFR walking can help improve the strength of muscles and overall physical abilities compared to a sham (placebo) version of BFR walking. Additionally, the study will look at how this type of exercise might affect muscle size, blood vessel health, and quality of life for these patients.

To be eligible for this trial, participants must have had a stroke at least six months ago and be diagnosed with sarcopenia. However, those who had a stroke within the last six months or have certain health issues, like very high blood pressure or implanted devices that could interfere with the study, will not be able to join. Participants can expect to take part in walking exercises using BFR techniques, and the study will help determine if this approach can effectively support recovery and improve their daily lives.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosed with chronic stroke (≥6 months post-stroke)
• • Diagnosed with sarcopenia, based on AWGS 2019 criteria
• Exclusion Criteria:
• • Stroke occurred within the past 6 months
• • Resting systolic blood pressure \> 200 mmHg
• • Resting diastolic blood pressure \> 100 mmHg
• • Presence of implanted electronic or metallic devices that interfere with blood flow restriction cuffs
• • Contraindication to bioelectrical impedance analysis (e.g., pacemaker, ICD)