Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis

Launched by ARMED FORCES INSTITUTE OF DENTISTRY, PAKISTAN · May 8, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how different root canal sealers affect pain after root canal therapy for patients with irreversible pulpitis, which is a serious tooth condition. The study will involve 62 patients who meet specific criteria, such as being healthy males aged 20-40 with a permanent first molar that has irreversible pulpitis but no swelling. Those who participate will be randomly assigned to receive one of two types of sealers during their treatment.

Participants can expect the procedure to be done under local anesthesia, meaning they won’t feel pain during the treatment. After the root canal, they will be asked to keep a pain diary for a week to record any discomfort they feel, using a simple scale from 0 (no pain) to 10 (severe pain). This will help the researchers understand which sealer results in less post-treatment pain. It's important for participants to attend follow-up appointments and provide written consent before joining the trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Permanent mandibular first molar with irreversible pulpitis without swelling and sinus.
• • 2. Patients of male gender between 20-40 years of age.
• • 3. Systemically healthy patients with no other co morbidity classified as ASA-I
• • 4. Patients who agree to attend for re call appointments and provide a written consent
• Exclusion Criteria:
• • - 1. Teeth with calcified canals and previously treated teeth. 2. Mandibular molars with reversible pulpitis. 3. Pregnant and lactating mothers. 4. Patients who are immunocompromised, anxious, mentally ill. 5. Cases of root fracture. 6. Patients who consumed analgesics 12-24 hrs before primary root canal therapy.
• • 7. Patients who are allergic to any of the medications being tested.