Creation of a Database of Healthy Subjects With 18FDG PET Brain Imaging as Part of the MOBILE Project (Multimodal Whole-Brain Imaging in Epilepsy)

Launched by ASSISTANCE PUBLIQUE HOPITAUX DE MARSEILLE · May 15, 2025

Keywords

ClinConnect Summary

The MOBILE project is a clinical trial that aims to better understand how the brain works in both healthy individuals and those with epilepsy. Specifically, this part of the project is focused on collecting brain imaging data from 30 healthy adults using a technique called 18F-FDG PET (Positron Emission Tomography). This imaging method helps scientists measure how the brain uses sugar for energy, which can give insights into brain activity and connectivity. The goal is to build a comprehensive database that will be shared with researchers to enhance our understanding of brain health and function.

To participate in this trial, you need to be between 18 and 65 years old and in good health, without any major illnesses or mental health concerns. You should not be on long-term medication and must not be pregnant or breastfeeding. If you qualify, you will undergo a PET scan that involves a small injection of a safe, radioactive substance to help visualize your brain activity. This trial is designed to be safe and will contribute valuable information to the scientific community, so your participation may help advance brain research for everyone.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Female or male, over 18 and under 65 years of age.
• • Subject free of any general illness, psychiatric disorders or infectious, inflammatory, tumoral, vascular, degenerative or traumatic pathology of the central nervous system, as determined on examination,
• • Subject not receiving chronic treatment, particularly psychotropic,
• • Subject with no history of alcoholism or drug addiction,
• • Subject with no contraindications to PET scintigraphic exploration (pregnancy and breast-feeding),
• • Subject with social security coverage,
• • Subject having read, understood and signed an informed consent form.
• Exclusion Criteria:
• • - Minors,
• • Pregnant or breast-feeding women,
• • Women of childbearing age without contraception,
• • Subjects presenting a contraindication to PET scintigraphic exploration,
• • adult subject to a legal protection measure, as provided for in L.1121-6 to L.1121-8 of the French Public Health Code.