Intra- and Interindividual Moderators of Prefrontal Excitability Investigated Using Simultaneous TMS With Neuroimaging

Launched by THE HONG KONG POLYTECHNIC UNIVERSITY · May 9, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring how a specific brain stimulation technique, called intermittent theta-burst stimulation (iTBS), affects the brain's activity in healthy adults. The researchers aim to understand how this non-drug treatment can help with mental health issues by looking closely at brain responses during the stimulation. They are using advanced technology that combines brain stimulation with imaging to get detailed pictures of how different areas of the brain respond to the treatment. This could help in developing better treatments for mental disorders in the future.

To participate in this study, you should be a healthy adult aged between 18 and 60. However, if you have any current or past mental health issues, substance abuse problems, or certain medical conditions, you may not be eligible. Participants will undergo sessions where they receive brain stimulation while being monitored with imaging technology, allowing researchers to see how the brain reacts in real-time. This study is an exciting opportunity to contribute to important research that could lead to advancements in mental health treatments.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • consider yourself healthy in general and aged 18-60
• Exclusion Criteria:
• • current internal illness;
• • current or former psychiatric or neurological illness;
• • current or former alcohol or substance abuse;
• • current or previous use of any psychotropic medication;
• • current or previous use of any illicit drug;
• • any ferromagnetic metal in your body;
• • known or possible pregnancy, including the situation when the first day of a
• • female's last menstrual period was more than 28 days ago; or
• • any contraindication to TMS as assessed by Rossi et al.'s (2011) screening questionnaire.