Improved Robotic-Assisted Radical Prostatectomy for Locally Advanced Prostate Cancer: Bladder Suspension and Preliminary Outcomes

Launched by FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL UNIVERSITY · May 12, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new approach to robotic-assisted surgery for men with locally advanced prostate cancer. The goal is to see if a technique that preserves a part of the bladder helps improve recovery of bladder function and control after surgery, compared to traditional methods. Researchers will look at how this modified surgery affects recovery, potential complications, and cancer outcomes. They hope to find better ways to prevent urinary incontinence, a common concern after prostate surgery.

To participate in this trial, men must have a confirmed diagnosis of high-risk prostate cancer, and they will need to have specific imaging tests done at the research center before surgery. Participants should be generally healthy and not have any serious health issues or other cancers. If you join, you can expect to undergo robotic-assisted surgery and be monitored closely for your recovery. The trial is currently recruiting participants, and it aims to provide valuable insights into improving surgical outcomes for prostate cancer patients.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • 1. prostate biopsy and clinical confirmation of high-risk prostate cancer (PSA \> 20 ng/mL, Gleason score ≥ 8, or cT stage ≥ T2c) followed by robotic-assisted radical prostatectomy
• • 2. multiparametric MRI (mpMRI) with a 3.0 T scanner for prostate or pelvic scans performed within 30 days before the operation at our center
• • 3. Eastern Cooperative Oncology Group (ECOG) performance status score between 0 and 1
• • 4. Complete clinical and prostate biopsy pathological data.
• • 5. General health is good, with no infections, autoimmune diseases, hematologic disorders, or other malignancies.
• Exclusion Criteria:
• • 1. Presence of surgical contraindications.
• • 2. refusal of enhanced mpMRI imaging.