Effectiveness of a Therapeutic Yoga Program on Fatigue and Related Variables in Patients With Chronic Fatigue Syndrome or Long Covid

Launched by UNIVERSITY OF SEVILLE · May 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a special yoga program can help reduce fatigue and improve overall well-being in people with Chronic Fatigue Syndrome/Myalgic Encephalitis (CFS/ME) or Long Covid. The program includes yoga, breathing exercises, and body awareness, and it will be compared to regular low-intensity exercises and standard medical care. The study lasts for twelve weeks and is conducted online, so participants can join from home. Researchers will also look at how the yoga program affects the body's nervous system by measuring heart rate variability, which can give insights into stress and relaxation.

To participate, individuals must be between 18 and 70 years old, have a diagnosis of CFS/ME or Long Covid, and be able to use a computer or mobile device for video sessions. They should also be comfortable with basic software tools and able to sit in a chair for about 45 minutes. It's important that participants do not have other serious health conditions that could explain their symptoms. This trial is currently recruiting participants, so if you or someone you know fits the criteria, it could be a great opportunity to explore a new approach to managing fatigue.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants must be over 18 and under 70 years of age (to minimize the presence of comorbidities).
• • Participants must meet the latest established diagnostic criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Post-Covid Syndrome, respectively.
• • Participants must have access to a computer, tablet, or mobile device with an internet connection to attend videoconference sessions.
• • Participants must have a mobile device compatible with the applications Cardiio: Heart Rate Monitor and Welltory, which will be used to measure heart rate (HR) and heart rate variability (HRV), respectively.
• • Participants must be able to remain seated in a chair for at least 45 continuous minutes.
• • Participants must have fluent comprehension of the Spanish language.
• • Any comorbid condition that could explain the symptomatology associated with the syndrome (such as post-infectious organ damage, heart disease, neurological disorders, cancer, severe psychiatric illness, or metabolic syndrome) must have been ruled out by a physician.
• Exclusion Criteria:
• • Recent suspicion of comorbid conditions that could explain the syndrome's associated symptoms, not yet ruled out by a qualified healthcare professional.
• • Inability to use basic software required for participation in the study (e.g., Microsoft Teams, completing a Google Forms questionnaire).
• • Unwillingness to make minor adjustments to daily habits.