Predicting Psychotic Relapse Using Speech-Based Early Detection

Launched by DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE · May 11, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new way to predict relapses in people with psychosis, which includes conditions like schizophrenia. Relapses are when symptoms return after a patient has been feeling better, and they can lead to serious issues like increased risk of suicide and difficulties in daily life. The researchers want to use a digital model that analyzes speech patterns to help identify when a patient might be at risk of relapsing. This study will involve participants from Early Psychosis Intervention clinics in Ontario and Quebec.

To be eligible for the trial, participants need to be at least 16 years old, have a diagnosis of a psychotic disorder (like schizophrenia), and be currently receiving treatment. They should also be able to speak either English or French. Participants will engage in assessments that include speech analysis, which could help improve how relapses are predicted in the future. This study is currently recruiting, and anyone interested should look into whether they meet the criteria to join.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age must be 16 years and older
• • Diagnosis must meet DSM-5 criteria for psychotic disorders, including schizophrenia, schizoaffective disorder, or related conditions
• • Fluency in English or French
• • Must be currently receiving treatment through an EPI program
• Exclusion Criteria:
• • Severe comorbid speech or language disorders (e.g., aphasia)
• • Primary diagnosis of non-psychotic disorders
• • Inability to provide consent or complete assessments