Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)

Launched by ABDIRAHMAN HASSAN OMAR · May 12, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating two different types of tissue used in surgery to repair a torn anterior cruciate ligament (ACL) in the knee, a common injury among active individuals. The study compares grafts taken from the quadriceps muscle at the front of the thigh and the semitendinosus muscle at the back. Researchers will analyze data from a national health registry to see how well patients recover after surgery, focusing on their knee function, activity levels, and whether they need any additional surgeries.

To participate in this study, you should be between the ages of 15 and 50 and have had a primary ACL reconstruction using either the quadriceps or semitendinosus graft. You also need to have been followed up for at least one year after your surgery with completed questionnaires about your knee health and activity. The trial is not currently recruiting participants, but if you meet these criteria, you may be eligible once it begins. This research aims to help improve recovery outcomes for patients who undergo ACL reconstruction.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Primary ACL reconstruction registered in the Danish Knee Ligament Reconstruction Registry (DKRR)
• • Known graft type: quadriceps tendon or semitendinosus tendon Minimum 1-year follow-up with completed patient-reported outcome measures (KOOS and/or Tegner score)
• • Age between 15 and 50 years at the time of surgery (optional subgroup analysis)
• Exclusion Criteria:
• • Revision ACL reconstruction
• • Multiligament knee reconstruction
• • Missing or incomplete PROMs or key clinical data