Improving Oral and Systemic Health in Individuals With Prediabetes Through Personalized Oral Hygiene Advice Provided by Dentists or by AI

Launched by THE UNIVERSITY OF HONG KONG · May 11, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how personalized oral hygiene advice, provided either by dentists or through artificial intelligence (AI), can help improve the oral and overall health of people with prediabetes. Prediabetes means that someone has higher-than-normal blood sugar levels but is not yet diagnosed with diabetes. This condition is linked to gum disease, which can worsen blood sugar levels and lead to other health issues. The trial aims to see if using AI to offer tailored advice on better home care for oral hygiene can lead to improvements in both gum health and blood sugar control, similar to what a dentist would provide.

To be eligible to participate, individuals must be over 18, mentally healthy, and able to provide consent. They should have at least six natural teeth in the front part of their mouth and be diagnosed with prediabetes, which is characterized by certain blood sugar measurements. Participants will need to speak, read, or understand Cantonese to fill out a satisfaction questionnaire and must be able to manage their own daily oral hygiene routine, like brushing and flossing their teeth. If you join the trial, you can expect to receive personalized advice on how to care for your teeth and gums, helping to improve your overall health while working with either a dental professional or AI technology.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - Subjects who are \>18 years of age and able to give informed consent.
• • - Subjects who are mentally and cognitively healthy.
• • - Subjects who have at least 6 anterior maxillary or mandibular natural teeth including incisors and canine.
• • - Subjects who are with prediabetic state with impaired HbA1c 5.7% to 6.4%, impaired fasting plasma glucose level 5.6mmol/L to 6.9 mmol/L and/or impaired plasma glucose level after 2h OGTT 7.8 mmol/L to 11.0 mmol/L.
• • - Subjects who can speak, read, or understand Cantonese to complete the satisfaction questionnaire.
• • - Subjects who can practice oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) daily on their own independently.
• Exclusion Criteria:
• • - Subjects who have less than 6 anterior maxillary or mandibular natural teeth with or without dental prostheses in those area.
• • - Subjects who are with a current diagnosis or clinical history of T2DM.
• • - Subjects who have mental illness, or similar problems that unable to complete the satisfaction questionnaire.
• • - Subjects who cannot perform oral hygiene procedure (regular tooth brushing and interdental cleansing/flossing/brushing) by any condition of oral cavity such as tumor or maxillomandibular fixation.