Registry of Pre-mixed Solutions in Critically Ill Patients on the Continuous Renal Replacement Therapy

Launched by VANTIVE HEALTH LLC · May 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the use of pre-mixed solutions for patients in critical condition who need continuous renal replacement therapy (CRRT), a treatment that helps replace the function of the kidneys. The researchers want to see how effective these pre-mixed solutions are in real hospital settings, gathering information from around 10 hospitals in China. The goal is to understand how well these solutions work for patients with kidney problems who are very ill.

To be eligible for the study, participants must be between 18 and 80 years old, currently in the intensive care unit (ICU), and need CRRT using one of the three pre-mixed solutions: Regiocit, Biphozyl, or Prismasol 2. However, patients who have chronic kidney failure requiring regular dialysis, those needing the solution for less than a day, or those with allergies to the solutions cannot participate. The trial is currently recruiting participants, and those involved can expect to provide important health information that will help researchers learn more about these treatments.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 ≤ age \< 80 years old.
• • Patients admitted to the intensive care unit (ICU) and in need of CRRT.
• * Patients are willing to receive CRRT with at least one of three pre-mixed solutions:
• • Regiocit, Biphozyl, or Prismasol 2.
• Exclusion Criteria:
• • Patients with chronic kidney failure who are receiving maintenance dialysis.
• • Patients expected to require the premixed solution for less than 24 hours.
• • Patients who are allergic or have contraindications to components of pre-mixed solutions, as determined by the investigators.
• • Patients who have participated in other interventional studies within the last 30 days.
• • Patients who are pregnant, breastfeeding, or abortus imminence.