Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal Edema

Launched by SINGAPORE EYE RESEARCH INSTITUTE · May 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new technology called the Terahertz (THz) scanning system to see how well it can evaluate corneal scars and corneal edema, which are conditions affecting the eye's clear front surface, the cornea. Researchers want to find out if this new scanning method can accurately measure the hydration levels in the cornea and track how these conditions change over time compared to traditional eye exams.

To participate, you need to be at least 21 years old and have either corneal scars or corneal edema, but not both at the same time. You should also be able to follow study instructions and keep your face steady for the scans. If you’re interested, you will undergo THz scanning followed by standard eye exams to gather detailed information about your condition. It’s important to know that individuals with active eye infections, pregnancy, or certain other health issues may not be eligible for this trial. This study is currently looking for participants, so if you think you qualify, it could be a great opportunity to contribute to eye health research!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Be at least 21 years of age.
• • Regardless of gender (Male/Female).
• • Regardless of race (Chinese/Malay/Indian/Eurasian/Others).
• • Willingness and ability to follow all instructions and comply with study schedule for study visit.
• • Patients with corneal endothelial dysfunction (Fuchs' endothelial dystrophy or other causes of bullous keratopathy) at any disease stage OR Patients with corneal scars from any cause, with the absence of corneal edema.
• • Ability to hold face sufficiently stable to undergo necessary scans.
• Exclusion Criteria:
• • Eyes with active inflammation or infection, or chronic ocular surface inflammation
• • Unable to give consent
• • Physically immobile/poor instructional compliance
• • PI determined
• • Pregnant/ breast feeding women