Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study

Launched by NATIONAL UNIVERSITY HOSPITAL, SINGAPORE · May 14, 2025

Keywords

ClinConnect Summary

The "Pioneering Advancements in Cardiocerebrovascular Interactions in the Asia pacFIC - Patent Foramen Ovale Study" is a clinical trial aimed at understanding patients with a specific heart condition called a Patent Foramen Ovale (PFO) who have also experienced a type of stroke known as ischemic stroke. This study will collect real-world information from patients in the Asia-Pacific region to learn more about their health, how they are treated, and the outcomes of those treatments. This research is important because it can help doctors improve care for individuals with these conditions.

To be eligible for this study, participants must be at least 18 years old and have had an acute ischemic stroke or a transient ischemic attack (a temporary stroke-like event). Additionally, they must be found to have a PFO through certain heart imaging tests. However, individuals who have had a different type of stroke or have not been followed for at least three months after their stroke will not be included. Participants in this trial can expect to share their health information and experiences, which will contribute to a better understanding of how to treat and manage conditions related to PFO and ischemic stroke. As of now, the study is not yet recruiting participants.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • 1. Subject has experienced acute ischemic stroke or transient ischemic attack
• • 2. Subject is screened with presence of PFO (right-to-left shunt) on appropriate cardiac imaging (transthoracic echocardiography and/or transesophageal echocardiography) or transcranial Doppler bubble study
• • 3. Age ≥18 years
• • Exclusion Criteria
• • 1. Stroke mimics, haemorrhagic stroke or cerebral venous thrombosis
• • 2. Subjects with less than 3 months of follow up