Optimizing Mango's Glycemic Impact: Investigating Mango Consumption Timing in Prediabetic Individuals

Launched by CLINICAL NUTRITION RESEARCH CENTER, ILLINOIS INSTITUTE OF TECHNOLOGY · May 20, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how eating mangoes can affect people who are at risk of developing diabetes, specifically those with prediabetes. Researchers want to understand the best times to eat mangoes and how the nutrients in mangoes are absorbed by the body. By studying these factors, they hope to learn more about how mangoes might help with blood sugar control and inflammation, which are important for managing prediabetes.

To participate in this study, you need to be between 20 and 60 years old, have a body mass index (BMI) between 25 and 35, and have specific blood sugar levels that indicate prediabetes. Participants should be generally healthy, not smoke, and be willing to follow certain dietary guidelines during the trial. If you join, you can expect to follow a schedule of visits and dietary restrictions to help researchers gather the necessary information. This study is currently active but not recruiting new participants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Be between 20-60 years old.
• • Have a BMI of 25-35 kilograms per square meter.
• • Have fasting blood glucose between 100-125 milligrams per deciliter or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
• • Be non-smokers for at least 12 months.
• • Be generally healthy, with no major organ-related diseases.
• • Not take medications or supplements that could interfere with the study.
• • Be able to follow study procedures, including dietary restrictions and scheduled visits.
• Exclusion Criteria:
• • Smoke, vape, or use marijuana.
• • Have allergies or intolerance to mangoes or study foods.
• • Have blood pressure above 160/100 millimeters of Mercury.
• • Have fasting blood glucose above 125 milligrams per deciliter.
• • Have a history of major heart disease, stroke, or cancer in the past five years.
• • Be pregnant, planning to become pregnant, or breastfeeding.
• • Take anti-inflammatory drugs or certain dietary supplements.
• • Have had major surgery or trauma in the past two months.
• • Follow extreme diets (e.g., vegan, Atkins).
• • Have used antibiotics in the last six weeks.
• • Have a history of eating disorders or substance abuse in the past two years.
• • Drink more than three cups of coffee or tea per day.
• • Have donated blood in the last three months.
• • Be professional athletes or do excessive exercise.
• • Have had weight changes of more than 11 pounds in the past two months.
• • Work overnight shifts.