Extent of Lymph Node Dissection for Advanced Right-Sided Colon Cance

Launched by SIXTH AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · May 22, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how many lymph nodes should be removed during surgery for patients with advanced right-sided colon cancer. The goal is to better understand how cancer spreads in this part of the colon and to find out the best surgical approach for treating it. The study will take place at multiple centers and aims to help doctors improve treatment for patients with this type of cancer.

To participate in the trial, you need to be between 18 and 75 years old and have a confirmed diagnosis of a specific type of colon cancer located in the right side of the colon. You should not have had any chemotherapy, radiation, or immunotherapy before the surgery. If you join the study, you'll receive care according to the trial's guidelines, and you'll need to sign a consent form agreeing to participate. It's important to know that there are some health conditions that may prevent you from being part of this trial, such as having other cancers or serious medical issues. This study aims to provide valuable information that can help improve treatment options for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age: 18-75 years
• • 2. Preoperative pathologic confirmation of adenocarcinoma
• • 3. Tumor located in the region from the ileocecal valve to the right one-third of the transverse colon
• • 4. American Society of Anesthesiologists (ASA) physical status classification I to III
• • 5. Patients who have not received preoperative radiotherapy, chemotherapy, or immunotherapy
• • 6. Preoperative imaging staging cT4N0M0 or cT3-4N+M0
• • 7. Willing to participate in the study and sign the informed consent form
• Exclusion Criteria:
• • 1. Past medical history of malignant tumor
• • 2. Patients with multiple primary tumors
• • 3. Patients with a history of inflammatory bowel disease or familial adenomatous polyposis
• • 4. Patients with distant metastasis
• • 5. Pregnant or breastfeeding women
• • 6. History of other previous major abdominal surgery
• • 7. Patients requiring emergency surgery (including tumor perforation, obstruction, hemorrhage, etc.)
• • 8. Those with other clinical and laboratory conditions deemed by the investigator to be inappropriate for participation in the trial