Remineralization Potential of PRG Barrier Coat Versus Fluoride Varnish in White Spot Lesions in Permanent Anterior Teeth of Children

Launched by CAIRO UNIVERSITY · May 15, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how well two treatments can help fix white spot lesions on the front teeth of children. These white spots are signs of early tooth decay, and the trial will compare a special coating called PRG Barrier Coat with fluoride varnish, which is a common treatment used to strengthen teeth. The goal is to see which treatment works better in helping these spots improve.

To participate in the trial, children aged 8 to 14 who are generally healthy can join if they have at least one white spot lesion that isn't too severe. It's important that they haven’t used any other tooth treatments in the last three months, and their parents must agree to participate by signing a consent form. The trial will take place soon, and participants can expect to receive either the PRG Barrier Coat or fluoride varnish treatment during the study. If a child has other dental issues, like cavities or is undergoing orthodontic treatment, they won't be eligible for this trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged 8-14 years with good health according to the American Society of Anesthesiologists (ASA-I).
• • Have at least one white spot lesion with International Caries Detection and Assessment System (ICDAS II) score one or two
• • Has not used any remineralizing agent in the former three months.
• • Parents who accept to sign informed consent.
• • Cooperative patients
• Exclusion Criteria:
• • Patients have caries or restorations in the labial surface.
• • Extrinsic or intrinsic stains.
• • patients under active orthodontic treatment.
• • Uncooperative patient.
• • Parents refuse to sign informed consent.
• • Medically unfit (other than ASAI).