Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic Rhinosinusitis

Launched by CAIRO UNIVERSITY · May 15, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating two treatments—photobiostimulation and pulsed electromagnetic field therapy—to see how they affect the quality of life for adults suffering from chronic rhinosinusitis, which is a long-term inflammation of the sinuses. The study aims to find out if these treatments can improve symptoms like headaches, nasal issues, and overall breathing function.

To participate in this trial, you need to be between 20 and 40 years old and have mild to moderate symptoms of chronic rhinosinusitis. You also need to have a confirmed allergy to common triggers like dust or pet dander. Unfortunately, some people won’t be eligible, such as those who are pregnant, have certain health conditions like high blood pressure or diabetes, or have taken specific medications recently. If you join, you can expect to receive one of the treatments and help researchers understand how effective these therapies are for improving life quality in people with your condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Participants suffering from mild to moderate symptoms (baseline Total nasal symptoms score ≤ 9).
• • 2. Subjects age range from 20 to 40 years old.
• • 3. Patients of both sexes.
• • 4. proven positive allergy test (skin prick test or multiple allergen simultaneous test) to any of the common perennial allergens such as dust mites, molds, insects, and animal dander within the last 12 months
• Exclusion Criteria:
• • Pregnant or breastfeeding women.
• • Patients with a definite deviated nasal septum, or history of operation within the last 6 months.
• • Hypertension, diabetes mellitus, malignancy, active pulmonary tuberculosis, active respiratory disease like asthma, or other systemic diseases.
• • Long-term use of corticosteroids or immunosuppressive agents.
• • Participation in another clinical study within 30 days.
• • Hyperthyroidism
• • Patients who had used antihistamines within 1 week, topical corticosteroids within 2 weeks, systemic corticosteroids within 4 weeks, anticholinergic drugs within 3 days, antileukotriene drugs within 1 week, decongestants within 3 days, tricyclic antidepressants or phenothiazines within 2 weeks, nonsteroidal analgesics within 2 weeks, and other drugs that the researchers believed were inappropriate.
• • Patients with Tattoos, moles and dark skin