Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings

Launched by MILOŠ POTKONJAK · May 16, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how well two different types of dressings help heal burn wounds in children. The dressings being compared are chitosan-based dressings, which come from a natural substance and may help with healing and fighting infection, and silver-based dressings, which are commonly used in burn care. The study will measure how quickly wounds heal, how much scarring occurs, the cost of treatment, and how the children and their families feel about their care.

To participate, children must be between 6 months and 17 years old and have a first or second-degree burn that is not too severe (meaning it doesn't cover more than 20% of their body). They should be admitted to the hospital within 72 hours of getting the burn and have a clean, non-infected wound. If eligible, participants will receive one of the dressings for their burn and will be monitored throughout the healing process. It’s important to note that children with certain health conditions or previous treatments may not be able to join the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age between 6 months and 17 years old
• • 2. Having a first or second-degree superficial burn that does not require excision and grafting
• • 3. Patients with a burn of less than 20% of the total body surface area (TBSA)
• • 4. Admission within 72 hours of burn injury
• • 5. First line of therapy is Burnshield® Dressing for the first 48 hours
• • 6. Clean non-infected wound as diagnosed by the attending physician
• • 7. Informed consent of the patient or caregiver
• Exclusion Criteria:
• • 1. Causes other than contact burn, flame or scald injuries (i.e., electrical, chemical or frostbite)
• • 2. Diabetes mellitus
• • 3. Significant cardiac, pulmonary, or renal insufficiency
• • 4. Severe hematologic disease, malignancy, hypo-immunity
• • 5. Wounds noted to be contaminated or infected
• • 6. Systemic inflammatory response syndrome (SIRS) or sepsis
• • 7. Moderate or severe respiratory tract or lungs burn injuries
• • 8. Previous treatment efforts such as previous debridement, silver sulfadiazine ointment or other topical agents (e.g.: oil, toothpaste, betadine, rivano)
• • 9. Being pregnant or breastfeeding
• • 10. Known sensitivity or allergy to one of the dressings or its components.