Vibration Applications After Total Knee Arthroplasty in Osteopenic Women

Launched by ISTINYE UNIVERSITY · May 16, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating how different types of vibration therapy can help improve recovery for women with low bone density (osteopenia) after they undergo total knee replacement surgery (TKA). The study will look at how these therapies affect various aspects of recovery, such as muscle strength, pain levels, joint movement, and overall function. Women who are scheduled for their first TKA due to knee arthritis and have specific bone density measurements may be eligible to participate.

Participants will be randomly assigned to one of three groups: one group will receive vibration therapy alone, another will combine vibration therapy with exercise, and a control group will continue with standard rehabilitation. All groups will meet for traditional rehabilitation sessions three times a week for four weeks after surgery, with vibration therapy starting later. By examining the effects of these different approaches, the researchers hope to find the best way to support recovery and improve the quality of life for women after knee surgery.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Scheduled to undergo unilateral, primary, cemented total knee arthroplasty (TKA) using a posterior cruciate ligament-sacrificing technique and medial parapatellar approach due to knee osteoarthritis
• • Ability to speak and understand Turkish
• • Ability to comprehend both verbal and written information
• • A T-score between -2.5 and -1 (i.e., -2.5 \< T-score \< -1) measured by DXA in the lumbar spine, total hip, or femoral neck within the past year
• Exclusion Criteria:
• • Scheduled for revision TKA
• • American Society of Anesthesiologists (ASA) physical status classification score higher than 3
• • History of major surgery on the limb to be operated
• • Presence of comorbid diseases such as rheumatoid arthritis or cancer
• • Presence of a neurological condition causing functional impairment
• • Diagnosed psychiatric disorder
• • Dementia
• • Disorders affecting the vestibular system
• • Having undergone anesthesia for any reason within the last month
• • Regular use of hypnotic or anxiolytic medications
• • Hearing or vision impairment not correctable by hearing aids or glasses
• • Presence of endocrine system disorders
• • Secondary osteoporosis or history of osteoporotic fracture
• • Metabolic bone diseases or chronic illnesses potentially affecting bone metabolism
• • Use of medications known to affect bone metabolism (e.g., menopausal hormone therapy, bisphosphonates, raloxifene, calcitonin, growth hormone, parathyroid hormones, corticosteroids) within 6 months prior to the start of the study