Bidirectional Cohort Study of Nanfang Spondyloarthritis

Launched by NANFANG HOSPITAL, SOUTHERN MEDICAL UNIVERSITY · May 16, 2025

Keywords

ClinConnect Summary

The "Nanfang SpA Bidirectional Specialized Disease Cohort" study is exploring how spondyloarthritis (SpA), including ankylosing spondylitis (AS), affects patients over time. This trial will collect important health information from patients who visit Nanfang Hospital in Southern China. Researchers will gather details about symptoms, lab tests, and imaging results like X-rays and MRIs during regular follow-up visits. They aim to create a comprehensive database that can help improve understanding and treatment of SpA in the future.

If you're between 10 and 59 years old and have been diagnosed with spondyloarthritis based on specific medical guidelines, you may be eligible to participate. Participants will not receive any experimental treatments but will contribute valuable health information that could aid in future research. It's important to note that pregnant women, those with certain severe health issues, or individuals judged unsuitable by the study team cannot take part. This study is currently recruiting participants and aims to support better care for patients with spondyloarthritis down the line.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1.Attended Nanfang Hospital, Southern Medical University, 2010-2030 2.Prospective cohort study component: subjects voluntarily participate with informed consent and sign an informed consent form 3.Retrospective cohort study: (i) patients who visited the hospital from April 2010 to April 2024 (and who will not return to the hospital at a later date) were exempted from informed consent; (ii) patients who visited the hospital from May 2024 to April 2025 were required to sign an informed consent 4.10 years old ≤ age ≤ 59 years old 5.Patients with a standardized diagnosis of spondyloarthritis by the following guidelines or diagnostic criteria, i.e., meeting one of the following diagnostic criteria: (1) 2009 ASAS classification criteria for axial spondyloarthritis; (2) 2011 ASAS classification criteria for peripheral spondyloarthritis
• Exclusion Criteria:
• • 1. Women who are pregnant, preparing for pregnancy or breastfeeding 2.Moderate to Severe Heart Failure (New York Heart Association Class 3-4) 3.Active peptic ulcers/bleeding 4.Judged by the investigator to be unsuitable for participation in this study