Lipid Emulsion for Reversal of Spinal Anesthesia in Ambulatory Surgery

Launched by ZAGAZIG UNIVERSITY · May 17, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the use of an intravenous lipid emulsion, a type of fat solution given through an IV, to help reverse the effects of spinal anesthesia in patients undergoing outpatient surgery. Spinal anesthesia is a method often used in surgeries like general, urology, gynecology, and orthopedic procedures, but it can sometimes lead to prolonged effects, such as difficulty moving or urinating. The goal of this study is to see if the lipid emulsion can help patients recover more quickly from the anesthesia.

To participate in this trial, individuals need to be between 21 and 70 years old, have a body mass index (BMI) of 35 or lower, and be in good overall health (classified as ASA I or II, meaning they have no serious health issues). They must also be scheduled for elective surgery using spinal anesthesia and be willing to cooperate throughout the study. However, those with allergies to the anesthesia used, certain medical conditions like bleeding disorders or liver disease, or a history of mental health issues won't be eligible. Participants can expect to receive the lipid emulsion after their surgery and will be monitored to see how well it helps with recovery from the anesthesia.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient acceptance.
• • Cooperative patient
• • Age 21-70 years old.
• • BMI ≤ 35 kg/m2
• • ASA I - II.
• • Elective ambulatory surgery under spinal anesthesia (general surgery, urology, gynecology, orthopedic surgery).
• Exclusion Criteria:
• • History of allergy to the LA agents used in this study,
• • Skin lesion at needle insertion site,
• • Those with bleeding disorders, sepsis, liver disease and psychiatric disorders
• • History of cognitive dysfunction or mental illness