Effects of Orthosis & Exercise on Spondylolisthesis
Launched by MEDIPOL UNIVERSITY · May 21, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of using a supportive device called an orthosis and a specific type of exercise on people with a condition called spondylolisthesis, which is when one of the bones in your lower back slips out of place. The goal is to see if these treatments can help improve pain, physical function, and overall quality of life. The trial will compare two types of exercises: stabilization exercises, which focus on strengthening the core muscles that support the spine, and conventional exercises, to see which is more effective when combined with the use of an orthosis.
To participate in this trial, you need to be between 18 and 65 years old and have been diagnosed with mild to moderate spondylolisthesis, but not be a candidate for surgery. You should be experiencing ongoing back pain for more than three months, but without any serious nerve problems. If you join, you can expect to follow a structured exercise program while wearing the orthosis, and your progress will be monitored through assessments of pain, physical abilities, and imaging tests. This study is important because it aims to provide more evidence on how these conservative treatments can help manage spondylolisthesis effectively.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Individuals aged 18-65
- • Individuals without indication for surgery
- • Individuals diagnosed with grade 1-2 spondylolysis
- • Individuals without neurological deficits
- • Individuals diagnosed with radicular pain or non-specific chronic low back pain for more than 3 months
- Exclusion Criteria:
- • Surgery recommended after diagnosis
- • History of lumbar surgery
- • Presence of rheumatic inflammatory diseases or diabetic polyneuropathy
- • Individuals with symptoms of cauda equina or ischemic heart disease
- • Presence of back pain with non-mechanical causes or non-radicular neuropathic pain
- • Having received this type of exercise therapy before
About Medipol University
Medipol University is a leading academic institution dedicated to advancing medical research and clinical innovation. With a strong emphasis on interdisciplinary collaboration, the university conducts rigorous clinical trials aimed at improving patient outcomes and enhancing healthcare practices. Leveraging state-of-the-art facilities and a team of experienced researchers and healthcare professionals, Medipol University is committed to contributing to the global medical community through ethical research and the development of novel therapeutic strategies. The institution fosters an environment of academic excellence and integrity, ensuring that all trials adhere to the highest standards of safety and efficacy.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported