Comparing Super High-flux and High-flux Dialyzer Performance Among Hemodialysis Patient With Sepsis : a Randomized Control Trial

Launched by NAVAMINDRADHIRAJ UNIVERSITY · May 19, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness of two different types of filters used in dialysis — the super high-flux dialyzer and the high-flux dialyzer — in patients with end-stage kidney disease (ESKD) who also have a serious infection called sepsis. The goal is to see if using the super high-flux dialyzer can improve patients' chances of recovery and reduce the risk of death associated with sepsis.

To be eligible for this trial, patients must be between the ages of 65 and 74 and have ESKD along with high levels of a substance in the blood called interleukin-6 (IL-6), which indicates inflammation. However, patients cannot take part if they need continuous kidney replacement therapy, are expected to pass away soon, or have had allergic reactions to the dialysis filters being tested. If you decide to participate, you'll be part of a study that is actively looking for ways to improve treatment outcomes for patients like you.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ESKD patients who have sepsis condition with high interleukin-6 (IL-6 \> 50 pg/ml)
• Exclusion Criteria:
• • Patients who needed dialysis with continuous kidney replacement therapy, vulnerable patient, include pregnant woman, patient who expected to pass away within the 24 hours.
• • Patients who have the history of allergic dialyzer reaction to dialyzer which used in this trial.