Comparing High Versus Low Dose of Oxytocin, in Gravida Women With BMI 30 and Above Which Are Undergoing Induction of Labor

Launched by HAEMEK MEDICAL CENTER, ISRAEL · May 17, 2025

Keywords

ClinConnect Summary

This clinical trial is designed to compare the effects of high and low doses of oxytocin, a hormone used to help induce or speed up labor, in women who are obese (with a body mass index or BMI of 30 and above). The researchers want to see if a higher dose of oxytocin (20 units in 1000 ml) is more effective than a lower dose (10 units in 1000 ml) for helping these women during labor. The trial is currently not recruiting participants, but once it begins, it will involve women who are between 37 to 42 weeks pregnant, have a single baby in the right position for delivery, and do not have any conditions that would prevent them from having a vaginal birth.

To be eligible for the study, women must meet certain criteria: they should be at term in their pregnancy and need oxytocin for either starting or enhancing labor. However, women who have had a previous cesarean section, are carrying more than one baby, or have serious fetal issues will not be included in the trial. Participants can expect to receive either the high or low dose of oxytocin and will be monitored throughout the process to compare the outcomes of both doses. This research aims to find the best approach to support labor in obese women, ultimately helping to improve their delivery experience.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women at term (37-42 weeks), requiring the use of oxytocin for induction of labor or for augmentation of labor.
• • BMI 30 and above
• • Viable singleton pregnancies
• • Cephalic presentation.
• • No contraindication for vaginal delivery
• Exclusion Criteria:
• • Women with previous cesarean delivery
• • Multiple pregnancy
• • Multiple fetal malformations
• • IUFD