CLOSM Trial: Groin Closure Using Layered Option for Suture Material
Launched by THE CLEVELAND CLINIC · May 22, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
The CLOSM Trial is a research study looking at the best way to close the groin area after vascular surgery, which is a type of procedure that helps treat blood vessel problems. In this trial, patients will be randomly assigned to have their groin closed with one of two types of stitches: Vicryl or PDS. If a patient is having surgery on both sides, they will receive one type of stitch on each side. This study is taking place at the Cleveland Clinic and is currently looking for participants.
To be eligible for this trial, you must be over 18 and scheduled for elective vascular surgery that involves making incisions in the groin. However, there are some people who cannot participate, including those under 18, pregnant women, or those needing emergency surgery. If you join the study, you will have a chance to help researchers understand which type of stitch leads to better healing after surgery. This is important because it could improve recovery for future patients undergoing similar procedures.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • All patients \> 18 years who undergo ELECTIVE vascular surgery that would require groin incisions
- • Patients with to undergo ELECTIVE bilateral groin incisions will be matched to receive closure with PDS in one groin and Vicryl in the other groin
- Exclusion Criteria:
- • 1. Age 17 or younger
- • 2. Prisoners
- • 3. Pregnant patients
- • 4. Emergent cases
- • 5. Active groin infection prior to intervention
- • 6. History of prior surgical groin access (re-operative groin)
- • 7. Groin closure after extracorporeal membrane oxygenation (ECMO)
About The Cleveland Clinic
The Cleveland Clinic is a renowned nonprofit academic medical center based in Cleveland, Ohio, recognized for its commitment to advancing healthcare through innovative research and clinical excellence. As a leading sponsor of clinical trials, the Cleveland Clinic leverages its multidisciplinary expertise and state-of-the-art facilities to conduct groundbreaking studies aimed at improving patient outcomes across a wide range of medical conditions. With a strong emphasis on patient-centered care, the institution fosters collaboration among researchers, clinicians, and patients to explore new treatments and therapies, contributing significantly to the global body of medical knowledge.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cleveland, Ohio, United States
Patients applied
Trial Officials
Francis Caputo, MD
Principal Investigator
The Cleveland Clinic
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported