Clinical and Cost-effectiveness of Learning Through Play Plus Culturally Adapted Cognitive Behaviour Therapy for Postnatal Depression in Nigeria
Launched by NOTTINGHAM TRENT UNIVERSITY · May 17, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying a new way to help mothers in Nigeria who are experiencing postnatal depression, which is a form of depression that can occur after giving birth. The trial will test an approach called Learning Through Play and Culturally Adapted Cognitive Behaviour Therapy (LTP+CaCBT). This method involves 12 sessions of fun, interactive play activities between mothers and their young children, guided by trained community health workers. The goal is to see if this intervention can improve the mental health of these mothers and, in turn, support the development of their children.
To be part of the study, mothers need to be between 18 and 49 years old, have a child aged 0-3 years, and show signs of depression. Participants will be chosen randomly to receive either the LTP+CaCBT intervention or standard care. Throughout the trial, mothers will be checked for their mental health at the beginning and again four and six months later. They will also share their experiences through interviews and group discussions. This research aims to find a helpful, culturally relevant treatment for postnatal depression in Nigeria, especially where mental health resources are limited.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 18 years and above
- • A mother with a child (0-3 years)
- • Able to provide full consent for their participation
- • A resident of the trial catchment areas
- • Able to complete a baseline assessment
- • Score 5 or above on Patient Health Questionnaire (PHQ-9)
- • available for follow-up at 4 and 6 months post-enrolment
- Exclusion Criteria:
- • Less than 18 years
- • Medical disorder that would prevent participation in a clinical trial, such as Tuberculosis or heart failure
- • Temporary residents are unlikely to be available for follow-up
- • Active suicidal ideation or any other severe mental disorder
- • Patients currently undergoing severe mental health treatment
- • Non-residents of the trial environs
- • Unable to consent
- • Unable to speak and understand English language
- • Other significant physical or learning disability
About Nottingham Trent University
Nottingham Trent University (NTU) is a prominent higher education institution in the UK, renowned for its commitment to advancing research and innovation across various disciplines, including healthcare and clinical trials. With a strong emphasis on interdisciplinary collaboration, NTU leverages its expertise in health sciences to design and conduct rigorous clinical studies aimed at improving patient outcomes and informing public health strategies. The university fosters a dynamic research environment, utilizing state-of-the-art facilities and methodologies to ensure ethical standards and scientific integrity in all its clinical trial endeavors.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported