Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control Trial

Launched by ANQING MUNICIPAL HOSPITAL · May 18, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a new pain medication called oliceridine compared to two commonly used options, morphine and sufentanil, for managing pain after lumbar spine surgery. The goal is to see how well these medications work and their safety for patients recovering from this type of surgery.

To participate in this trial, individuals must be between 18 and 65 years old and scheduled for lumbar spine surgery, with a physical health status classified as ASA grades I to III, indicating they are generally healthy to moderately ill. Participants in the study will receive one of the three medications and will be monitored for their pain levels at various times after surgery, as well as any side effects they might experience. This trial aims to provide valuable information on pain management options for patients undergoing lumbar surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Lumbar spine surgery with ASA grades I-III
• • Aged 18-65 years
• • Ethically, the patient voluntarily accepted this trial and signed the informed consent form
• Exclusion Criteria:
• • Severe respiratory and circulatory system diseases
• • Nervous system disease
• • Mental and psychological disorders
• • Abnormal liver and kidney functions
• • Participated in another drug clinical research within the past 30 days