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Search / Trial NCT06991816

The Brain&Senses Study

Launched by UNIVERSITY OF CAMPANIA LUIGI VANVITELLI · May 18, 2025

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Cognitive Decline Smell Loss Vertigo/ Dizziness Hearing Loss

ClinConnect Summary

The Brain&Senses Study is a research project designed to understand how problems with senses like smell, hearing, and balance affect thinking abilities and overall quality of life in older adults. Specifically, it looks at individuals aged 60 to 85 who are generally in good health and do not have serious psychiatric disorders. Over the course of five years, participants will undergo evaluations by specialists, including neurologists and hearing doctors, who will perform tests related to their senses. This study aims to discover if losing one sense, like smell or hearing, impacts brain functions and emotional well-being more than others.

To be eligible, participants should be between 60 and 85 years old, in good health, and able to commit to the five-year follow-up. However, individuals with certain medical conditions, like serious nasal or ear problems, recent strokes, or significant head injuries, won't be able to participate. If you join the study, you can expect to undergo various sensory tests and contribute to valuable research that could improve understanding of how sensory issues affect cognitive health in older adults.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients between 60 and 85 years of age
  • in general good health
  • the absence of known severe psychiatric disorders
  • available to be included in the study and
  • to follow the 5-year follow-up.
  • Exclusion Criteria:
  • Obstructive nasal problems
  • Previous endoscopic nose + paranasal sinus surgery
  • Chronic use of cortisone spray and/or systemic
  • Subjects with previous stroke and outcomes
  • Subjects with history of stroke in the last 3 years without outcomes
  • Head trauma in the last 24 months
  • Previous ear surgery
  • Patients who have been exposed to chemical agents without protection for work, e.g. carpenters
  • previous Covid with outcomes (olfactory, vestibular, auditory and cognitive "brain fog")

About University Of Campania Luigi Vanvitelli

The University of Campania Luigi Vanvitelli is a distinguished academic institution located in Italy, renowned for its commitment to advancing medical research and improving healthcare outcomes. As a clinical trial sponsor, the university leverages its extensive expertise in biomedical sciences to conduct innovative studies that address critical health challenges. With a focus on ethical standards and patient safety, the university collaborates with various healthcare professionals and research entities to facilitate groundbreaking clinical investigations, ultimately contributing to the development of new therapies and enhancing medical knowledge.

Locations

Naples, Campania, Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported