The Effect of Cap-assisted Water Exchange Colonoscopy on Straight Passage of the Colonoscope Through the Sigmoid Colon, Without Loop Formation

Launched by FUDAN UNIVERSITY · May 20, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new technique to help doctors perform a colonoscopy, which is a procedure used to examine the inside of the colon. Specifically, the trial is comparing different methods of guiding the colonoscope (the tube used in the procedure) through a part of the colon called the sigmoid colon. The researchers want to see if using a cap attached to the colonoscope can help it move through this area more easily, without creating loops that can make the procedure harder or less effective.

To be eligible for this study, participants should be between the ages of 18 and 80 and will need to have the colonoscopy done with sedation to ensure comfort. However, people with certain health issues, like a history of colorectal surgery, known cancer, or specific bowel conditions, cannot participate. If you join the study, you can expect to be randomly assigned to one of the different methods being tested, but you won’t know which method you are receiving. The trial is not yet recruiting participants, so keep an eye out for updates if you’re interested!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • aged 18-80 years
• • sedation colonoscopy
• Exclusion Criteria:
• • History of colorectal surgery
• • Clinical suspicion of, or pathologically confirmed, colorectal cancer
• • Presence of any "alarm" symptom or sign-hematochezia, melena, unexplained anemia or weight loss, palpable abdominal mass, or a positive digital rectal examination
• • Pregnancy or lactation
• • Known or suspected gastrointestinal obstruction
• • Diagnosed inflammatory bowel disease
• • Use of antiplatelet or anticoagulant therapy (e.g., aspirin, warfarin) within 7 days before colonoscopy or any documented coagulation disorder
• • Current enrolment in another clinical study or participation in any clinical trial within the previous 60 days
• • Requirement for emergency colonoscopy
• • Any other condition that, in the investigators' judgment, renders the patient unsuitable for inclusion in the study