Cerebellar Transcranial Alternating Current Stimulation (tACS) to Modulate Parkinson's Disease Tremor

Launched by UNIVERSITÄTSKLINIKUM HAMBURG-EPPENDORF · May 19, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to help people with Parkinson's disease (PD) manage their hand tremors, which can be difficult to control with traditional treatments. The researchers are testing a method called transcranial alternating current stimulation (tACS), which is a non-invasive technique that uses gentle electrical currents to stimulate the brain. What makes this study unique is that the stimulation is synchronized with the patient's own tremor, potentially providing better relief.

To participate in this trial, individuals must be between the ages of 65 and 74 and have a clinical diagnosis of Parkinson's disease, showing moderate to severe hand tremors. Those interested will need to give written consent and should not have other serious neurological or psychiatric conditions, heart pacemakers, or metal implants. The trial is currently recruiting participants, and those who join can expect to receive this innovative treatment while helping researchers understand its effectiveness in reducing tremors associated with Parkinson’s disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinical diagnosis of Parkinson's disease based on UK Brain Bank criteria
• • Patient exhibiting moderate to severe hand tremor
• • Provision written informed consent by the patient
• Exclusion Criteria:
• • History of other neurological disorders such as vascular malformations, ischemic or haemorrhagic stroke, cerebral neoplasia, epilepsy, or major psychiatric illness
• • Existence of heart pacemaker or metal implants in the body
• • Pregnancy