Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm

Launched by RENJI HOSPITAL · May 20, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a condition called myocardial fibrosis, which can occur after a heart attack (specifically, a type of heart attack known as STEMI or NSTEMI) that leads to the development of a ventricular aneurysm—a bulge in the heart's wall. Researchers will use a special imaging technique called 18F-FAPI PET/CT to get a better understanding of this condition in patients who have experienced a heart attack and have a ventricular aneurysm. The trial aims to see how the fibrosis in the heart relates to the patients' health outcomes over time.

To participate in this study, you need to be between 18 and 75 years old, have been diagnosed with a heart attack, and will be undergoing specific heart treatments. The trial is open to both men and women. During the study, participants will receive the PET/CT scan while in the hospital and will have follow-up heart tests, including echocardiograms, to monitor their heart health. It’s important to note that individuals who are under 18, pregnant, breastfeeding, or have had allergies to imaging agents cannot participate. This research could help improve understanding and treatment of heart conditions following a heart attack.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18-75 years old
• • Diagnosed with STEMI or NSTEMI (ACC/AHA guidelines)
• • Half male and half female
• • Undergo CAG and PCI treatment;
• • Receive either echocardiography or CMR to identify a ventricular aneurysm;
• • Written informed consent
• Exclusion Criteria:
• • Patients under the age of 18 years old;
• • Patients who are pregnant/breastfeeding;
• • Patients who has a previous history of allergy to radio tracers.